Hydroxypropyl betacyclodextrin - The use of ecdysterone

Origin

This product is a kind of active substance extracted from the whole grass of Cyanotis, arachnoidea, C, B, Clarke, which can promote the molting metamorphosis of silkworm. According to dry calculation, it contains B-molting hormone [C27H4407], which is not less than 90%.

Main parameters

Traits

The product is light yellow crystalline powder, odorless, with hygroscopicity, the color gradually darkens after exposure to light.

It is easily soluble in ethanol, slightly soluble in acetone, slightly soluble in ethyl acetate chloroform and hot water, and almost insoluble in ether

Pharmacological action

Ecdysone has physiological activities such as promoting protein synthesis, eliminating cholesterol in the body, lowering blood lipids, and controlling blood sugar rise in the human body, and has been used clinically. Folk use for rheumatoid arthritis.hritis.

Identify

1. Take a small amount of the product, add sulfuric acid to dissolve, should be reddish-brown.

⒉ Take a small amount of the product, add ethanol to dissolve, add 1-2 drops of ferric chloride test solution, should show dark green.

Comprehensive utilization

Preparation and application: Since its advent in 1976, deuteroecdysone has been developed irregularly as tablets, injections and plasts, and has a good effect on patients with rheumatism and arthritis with different symptoms. It has great potential application value in medicine.

Specific use

Use

1、In sericulture, it is used to shorten the age of silkworms, arrange the clusters neatly, and promote the spinning of silk cocoons;

2、In the aquaculture industry, shrimp, crab and ground insect breeding is also widely used;

3、In cosmetics, ecdysone is also used as a special additive;

4、Ecdysone can affect the entire development stage of insects from hatching larvae to adults, so it controls or kills agricultural pests, and it has been developed and applied as a third-generation pesticide;

5、Ecdysone also has some effects on the physiological process of crops, and has good prospects for development and application in crop yield auxiliaries.

6、The application in the human body: it has the ability to regulate blood glucose ester, promote the synthesis of collagen, anti-arrhythmia, anti-fatigue, regulate blood glucose, promote cell growth, stimulate dermal cell division.

Various pharmacological effects of ecdysterone: promoting RNA and protein synthesis; Affect glucose metabolism; Promote lipid metabolism; Immune regulation; Affect the central nervous system, etc. There is evidence that ecdysterone has high medicinal value.

Hydroxypropyl betacyclodextrin can solve the water solubility problem of insoluble or insoluble drugs (including plant extracts).

Through molecular embedding, the product can improve drug solubility and control drug release speed, improve drug bioavailability, enhance drug stability, and reduce drug toxicity.